MODULATORS :: APPLICATIONS :: Vibrational Circular Dichroism (VCD)

Vibrational circular dichroism (VCD) is the differential absorption between left and right circularly polarized light (A = AL – AR). It is a measurement of the optical activity for chiral molecules.

SETUP






PEM Setting: quarter-wave retardation (/4)
Polarization Modulation: right and left circular polarization
Lock-in reference: PEM’s 1st harmonic


APPLICATIONS
Structural study and chiral analysis in chemistry; biochemistry; drug and pharmaceutical industry

TYPICAL HEAD ASSEMBLIES

RESOURCES

Vibrational Circular Dichroism Application Note                  PEM Based VCD Spectroscopy    PEM Newsletter #5: PEM-Based Vibrational Circular Dichroism

II/ZS37
II/CF57

FURTHER READING
L. A. Nafie, T. A. Keiderling and P. J. Stephens, J. Amer. Chem. Soc. 98, 2715 (1976)

T. A. Keiderling, in Practical Fourier Transform Infrared Spectroscopy, ed. J. R. Ferraro and K. Krishnan, (Academic, San Diego, 1990) p.203

L. A. Nafie and D. W. Vidrine in Fourier Transform Infrared Spectroscopy, Vol. 3, J. R. Ferraro and L. J. Basile, Eds., (Academic, New York, 1982) p. 83

D. Tsankov, T. Eggimann and H. Weiser, Appl. Spectr. 49, 132 (1995)